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  • 19685-09-7_10-Hydroxycamptothecin

    Product Name: 10-Hydroxycamptothecin
    CAS No.: 19685-09-7
    Synonyms: SN38;HCPT;Ampule;10-HCPT;NSC 107124;
    HYDROCAMPTOTHECINE;hydroxy-camptotheci;
    HYDROXYCAMPTOTHECIN;Irinotecan USP RC A;
    10-HYDROCAMPTOTHECIN
    Formula: C20H16N2O5
    Formula Weight: 364.4
    Appearance: Pale yellow powder or pale yellow crystalline powder
    Structure: structue of Camptothecin
    Assay: min. 99.0%
    Melting point: 265-270°C
    Density: 1.60
    Safety Information of 10-Hydroxycamptothecin (cas number:19685-09-7) as below:
    Safety Statements: 24/25
    WGK Germany: 3
    RIDADR: NONH for all modes of transport
    HS Code: 29349990
    Packing & Storage: Packing with IATA required carton with 5kg/carton, or as customer required. Stored in a cool, dry and dark place, shelf life 24 months.
    Application:
    1. (S)-10-Hydroxycamptothecin is the natural starting material of Irinotecan HCl.
    2. (S)-10-Hydroxycamptothecin is the natural starting ingredient of 7-Ethyl-10-Hydroxycamptothecin(SN-38).
    3. (S)-10-Hydroxycamptothecin is the natural starting ingredient of Topotecan HCl
    4. This compound 10-hydroxycamptothecin is a featured product for Apoptosis research.
    Function:
    10-hydroxycamptothecin showed remarkable anticancer activity in preliminary clinical trials by inhibiting the DNA enzyme topoisomerase I (topo I). (S)-10-Hydroxycamptothecin is a clinical therapy agent against hepatoma.
    Natural origins of camptothecin:
    1. Camptotheca acuminata (Camptotheca, Happy tree), a tree native to Hunan ,Guangxi, Sichuan province of China. Camptotheca acuminata used as a cancer treatment in Traditional Chinese Medicine.Generally, the leaves and the fruits of happy tree are applied for the extraction of camptothecin.
    2. Nothapodytes pittosporoides(Mappia), a tree wild spread in Hunan ,Guangxi, Sichuan province of China. The root of the tree is applied for the extraction of campothecin, most of this origin is applied for R&D.
    Get in touch with us for premium 10-Hydroxycamptothecin (cas number:19685-09-7)! We are a reliable Manufacturer, Supplier and Exporter of 10-Hydroxycamptothecin (cas number:19685-09-7). The product is widely used as a topoisomerase inhibitor for cancer therapy. Buyers are free to place orders of the product with us and we ensure the quality.
    downstream product 7-Ethyl-10-hydroxycamptothecin
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